Human white blood cells use molecular paddles to swim

ScienceDaily | Sep 15, 2020 at 7:37 PM
  • The actin cytoskeleton is widely accepted as the molecular engine propelling cell crawling.
  • The new findings demonstrate that actin-bound transmembrane proteins paddle and propel the cell forward, whereas freely diffusing transmembrane proteins hinder swimming.
  • Moving forward, the researchers plan to investigate the functions of molecular paddling in various environments and assess whether other types of cells use this mode of migration.