How cells use mechanical tension sensors to interact with their environment

ScienceDaily | Oct 26, 2020 at 8:32 PM
  • A good deal of actin’s activity is based on mechanical signaling; it appears to somehow sense physical feedback from the environment and respond accordingly.
  • By literally stretching individual actin filaments, the researchers determined a process by which actin transmits cellular mechanical messages to other proteins.
  • Alushin notes that, while α-catenin and its floppy tail may eventually become an appealing target for clinical therapies, the new findings are first and foremost a coup for the burgeoning field of mechanobiology.