Novel adoptive cell transfer method shortens timeline for T-cell manufacture

ScienceDaily | Oct 30, 2020 at 8:05 PM
  • In the September issue of Cancer Research, Hannah Knochelmann, a student in the Medical Scientist Training Program at the Medical University of South Carolina (MUSC) and researcher in Chrystal Paulos’ laboratory, teamed up with investigators at three different NCI-designated cancer centers — MUSC Hollings Cancer Center, Emory Winship and the James at The Ohio State University — to report a new approach to generate T-cells faster for patients in the near future.
  • Adoptive T-cell transfer therapy, which is the transfer of therapeutic T-cells into a patient, is used in only a handful of institutions around the world.
  • More cells were actually equally or less effective compared with fewer Th17 cells expanded only four days.