In the blood: Which antibodies best neutralize the coronavirus in COVID-19 patients?

EurekAlert! | Dec 12, 2021 at 1:00 AM
  • The COVID-19 pandemic has now claimed over 2 million deaths worldwide, and this number is only increasing.
  • Presence of antibodies specific to the S protein means there is a higher amount of virus-neutralizing activity while antibodies specific to N protein indicate the presence of previous SARS-CoV-2 infection.
  • The team developed assays using three common antibodies (IgG, IgM, and IgA), each of them split into isotypes that bind specifically to five antigens (three parts of the S protein, including the receptor binding domain [RBD], the full S protein, and the full N protein).